Article
Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia.
Molecular psychiatry - 1 Nov 2007
Christoforou A, Le Hellard S, Thomson P A, Morris S W, Tenesa A, Pickard B S, Wray N R, Muir W J, Blackwood D H, Porteous D J, Evans K L
Abstract excerpt
Several independent linkage studies have identified chromosome 4p15-p16 as a putative region of susceptibility for bipolar disorder (BP), schizophrenia (SCZ) and related phenotypes. Previously, we identified two subregions (B and D) of the 4p15-p16 region that are shared by three of four 4p-linked families examined. Here, we describe a large-scale association analysis of regions B and D (3.8 and 4.5 Mb,...
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