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Article

Variant metabolizing gene alleles determine the genotoxicity of benzo[a]pyrene.

Environmental and molecular mutagenesis - 1 Jan 2001

Salama S A, Sierra-Torres C H, Oh H Y, Hamada F A, Au W W

Abstract excerpt

Understanding the mechanisms involved with genetic susceptibility to environmental disease is of major interest to the scientific community. We have conducted an in vitro study to elucidate the involvement of polymorphic metabolizing genes on the genotoxicity of benzo[a]pyrene (BP). Blood samples from 38 donors were treated with BP and the induction of sister chromatid exchanges (SCE) and chromosome aberrations...

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Source

Identifiers

PMID: 11170238
DOI: 10.1002/1098-2280(2001)37:1<17::aid-em1002>3.0.co;2-f

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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