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Article

Effects of metabolic genotypes on intermediary biomarkers in subjects exposed to PAHS: results from the EXPAH study.

Mutation research - 1 Jul 2007

Garte Seymour, Taioli Emanuela, Raimondi Sara, Paracchini Valentina, Binkova Blanka, Sram Radim J, Kalina Ivan, Popov Todor A, Singh Rajinder, Farmer Peter B

Abstract excerpt

Data from the EXPAH project on PAH exposure and intermediary biomarkers were analyzed with respect to individual genotypes at seven metabolic gene loci. The GSTM1 null allele was associated with significantly higher levels of two biomarkers, malondialdehyde-2'-deoxyguanosine and benzo[a]pyrene DNA adducts in the total population from three Central and Eastern European countries. The CYP1B1 Leu/Val variant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP1B1

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Share to Glutathione S-Transferase pi

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Source

Identifiers

PMID: 17403528
DOI: 10.1016/j.mrfmmm.2007.02.017

Genes

GSTM1
GSTP1
GSTT1
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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