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Article

Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.

European journal of dermatology : EJD - 1 May 2011

Jonca Nathalie, Leclerc Emilie A, Caubet Cécile, Simon Michel, Guerrin Marina, Serre Guy

Abstract excerpt

Corneodesmosin (CDSN) was identified 20 years ago by raising monoclonal antibodies against human plantar stratum corneum. The protein is specific to corneodesmosomes, cell-junction structures that, in humans, are found in the epidermis, the hard palate epithelium, and the inner root sheath of the hair follicles. Synthesized by the granular keratinocytes and secreted via the lamellar bodies, CDSN is incorporated...

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Source

Identifiers

PMID: 21628128
DOI: 10.1684/ejd.2011.1264

Genes

CDSN

Provenance

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