Article
New polymorphisms in the interleukin-10 gene--relationships to myocardial infarction.
European journal of clinical investigation - 1 Jan 2001
Donger C, Georges J L, Nicaud V, Morrison C, Evans A, Kee F, Arveiler D, Tiret L, Cambien F
Abstract excerpt
BACKGROUND: Interleukin-10 (IL-10) is a cytokine with anti-inflammatory and B-cell-stimulating activity. IL-10 is expressed in human atherosclerotic plaques and recent studies have shown the involvement of IL-10 in the atherosclerotic process. Therefore, we hypothesized that polymorphisms in the IL-10 gene might be associated with a predisposition to coronary heart disease. MATERIALS AND METHODS: To identify new...
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