Article
Classical and neoclassical approaches to the genetic analysis of alcohol-related phenotypes.
Alcoholism, clinical and experimental research - 1 Aug 1995
Dudek B C, Tritto T
Abstract excerpt
Theoretical descriptions are given for two breeding methods in animal genetics that might be of use in alcohol research. These methods are marker-based selection and marker-based development of congenic strains, both using DNA markers such as polymerase chain reaction-detectable polymorphisms as the criteria for breeding. Such designs would utilize these markers as indicators of adjacent Quantitative Trait Loci...
Topics
- Alcoholism
- Animals
- Female
- Genetic Markers
- Male
- Mice
- Mice, Inbred Strains
- Models, Genetic
- Motor Activity
- Phenotype
- Selection, Genetic
