Article
The cortical hem regulates the size and patterning of neocortex.
Development (Cambridge, England) - 1 Jul 2014
Caronia-Brown Giuliana, Yoshida Michio, Gulden Forrest, Assimacopoulos Stavroula, Grove Elizabeth A
Abstract excerpt
The cortical hem, a source of Wingless-related (WNT) and bone morphogenetic protein (BMP) signaling in the dorsomedial telencephalon, is the embryonic organizer for the hippocampus. Whether the hem is a major regulator of cortical patterning outside the hippocampus has not been investigated. We examined regional organization across the entire cerebral cortex in mice genetically engineered to lack the hem....
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