Article
Disulfide bridge reorganization induced by proline mutations in maurotoxin.
FEBS letters - 2 Feb 2001
Carlier E, Fajloun Z, Mansuelle P, Fathallah M, Mosbah A, Oughideni R, Sandoz G, Di Luccio E, Geib S, Regaya I, Brocard J, Rochat H, Darbon H, Devaux C, Sabatier J M, de Waard M
Abstract excerpt
Maurotoxin (MTX) is a 34-residue toxin that has been isolated from the venom of the chactidae scorpion Scorpio maurus palmatus, and characterized. Together with Pi1 and HsTx1, MTX belongs to a family of short-chain four-disulfide-bridged scorpion toxins acting on potassium channels. However, contrary to other members of this family, MTX exhibits an uncommon disulfide bridge organization of the type C1-C5, C2-C6,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.