Article

A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor.

2021-07-03

Abstract excerpt

<h4>Background: </h4> and purpose. Venomous animals express numerous Kunitz-type peptides. The mambaquaretin-1 (MQ1) recently identified from the Dendroaspis angusticeps venom is the most selective antagonist of the arginine-vasopressin V2 receptor (V2R) and the unique Kunitz-type peptide active on a GPCR. We aimed to exploit other mamba venoms to enlarge the V2R-Kunitz peptide family and get insight into the MQ1...

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Literature Corpus work: dc416bff-adb6-5877-97e7-4767c78f0ab7
DOI: 10.22541/au.162531232.27386282/v1

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