Article
Molecular and cytogenetic alterations in early stage of carcinogenesis of human lung.
Cancer letters - 1 Jan 2001
Cheng S, Gao Y, Dong X, Lu Y, An Q, Tong T, Wang Y
Abstract excerpt
In an attempt to reveal the genetic and epigenetic abnormalities in early stage of carcinogenesis of human lung cancer, a human bronchial epithelial cell line was immortalized by transfection with the Simian virus early region genes (SV40T); the biological features of the stable transfected cells were compared to human non-small cell lung cancer (NSCLC) specimens. The immortalized bronchial epithelial cells did...
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