Article
The role of pyridoxal phosphate in the function of EspB, a protein secreted by enteropathogenic Escherichia coli.
FEBS letters - 12 Jan 2001
Taylor K A, O'Connell C B, Thompson R, Donnenberg M S
Abstract excerpt
The sequence of EspB, a secreted protein required for virulence of enteropathogenic Escherichia coli (EPEC), reveals a motif common to enzymes that bind pyridoxal phosphate. Pyridoxal phosphate was not found by fluorometry in concentrated supernatants of EPEC cultures that contain EspB. Plasmids containing cloned espB, in which the lysine residue conserved in the motif was substituted with either an arginine or...
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