Article
Attaching and effacing of host cells by enteropathogenic Escherichia coli in the absence of detectable tyrosine kinase mediated signal transduction.
Microbial pathogenesis - 1 Sept 1996
Rabinowitz R P, Lai L C, Jarvis K, McDaniel T K, Kaper J B, Stone K D, Donnenberg M S
Abstract excerpt
An unusual mutant of enteropathogenic E. coli (EPEC), deficient in its ability to invade host cells, was evaluated. The gene interrupted by the transposon in this mutant was located within a region of the EPEC chromosome devoted to secretion of proteins required for signal transduction. The mutant did not secrete detectable levels of the EspB protein, previously shown to be required for attaching and effacing,...
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