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Article

Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.

Journal of bacteriology - 1 Aug 1998

Yang Y, Zhao G, Man T K, Winkler M E

Abstract excerpt

We show that epd (gapB) mutants lacking an erythrose 4-phosphate (E4P) dehydrogenase are impaired for growth on some media and contain less pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP) than their epd+ parent. In contrast to a previous report, we found that gapA epd double mutants lacking the glyceraldehyde 3-phosphate and E4P dehydrogenases are auxotrophic for pyridoxine. These results...

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Identifiers

PMID: 9696782
DOI: 10.1128/JB.180.16.4294-4299.1998
PMCID: PMC107430

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