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Article

Inorganic polyphosphate in Escherichia coli: the phosphate regulon and the stringent response.

Journal of bacteriology - 1 Apr 1998

Rao N N, Liu S, Kornberg A

Abstract excerpt

Escherichia coli transiently accumulates large amounts of inorganic polyphosphate (polyP), up to 20 mM in phosphate residues (Pi), in media deficient in both Pi and amino acids. This transient accumulation is preceded by the appearance of nucleotides ppGpp and pppGpp, generated in response to nutritional stresses. Mutants which lack PhoB, the response regulator of the phosphate regulon, do not accumulate polyP...

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Identifiers

PMID: 9555903
DOI: 10.1128/JB.180.8.2186-2193.1998
PMCID: PMC107147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inorganic polyphosphate in Escherichia coli: the phosphate regulon and the stringent response.PMID 9555903Read ↗

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Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift.Semantic proximity Read ↗

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Accumulation of Polyphosphate in Lactobacillus spp. and Its Involvement in Stress ResistanceSemantic proximity Read ↗

PhoB Activates Escherichia coli O157:H7 Virulence Factors in Response to Inorganic Phosphate LimitationSemantic proximity Read ↗

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