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Article

Activated Fyn phosphorylates alpha-synuclein at tyrosine residue 125.

Biochemical and biophysical research communications - 2 Feb 2001

Nakamura T, Yamashita H, Takahashi T, Nakamura S

Abstract excerpt

alpha-Synuclein is a presynaptic protein of unknown function that has been implicated in the pathogenesis of several neurodegenerative diseases, including Parkinson's and Alzheimer's diseases. To gain insight into the functions of alpha-synuclein, we sought protein kinases that phosphorylate alpha-synuclein in the central nervous system. In contrast to Lyn, PYK2, FAK, MAPK/ERK1, SAPK/JNK, and Cdk5, only Fyn could...

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Identifiers

PMID: 11162638
DOI: 10.1006/bbrc.2000.4253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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