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Article

Cathepsin B as a soluble marker to monitor the phenotypic stability of engineered cartilage.

Biomaterials - 1 May 2003

Grigolo Brunella, Roseti Livia, Fiorini Mauro, Piacentini Anna, De Franceschi Luciana, Facchini Andrea

Abstract excerpt

The clinical need for improved human autologous chondrocyte transplantation has motivated the use of different biomaterials, which are aimed at fixing the cells in the defect area and permit their proliferation and differentiation. The maintenance of the original phenotype by isolated chondrocytes grown in vitro is an important requisite for their use in repairing damaged articular cartilage. The methods to...

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PMID: 12593957
DOI: 10.1016/s0142-9612(02)00569-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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