Article
Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage.
The Journal of clinical investigation - 1 Mar 1993
Aigner T, Bertling W, Stöss H, Weseloh G, von der Mark K
Abstract excerpt
Normal and osteoarthritic human articular cartilage was investigated by in situ hybridization for expression patterns of the fibrillar collagens type I, II, and III to evaluate phenotypic changes of articular chondrocytes related to the disease. In 11 out of 20 samples, a defined subset of chondr...
Topics
- Adult
- Antibodies
- Antibodies, Monoclonal
- Cartilage, Articular
- Collagen
- Epitopes
- Extracellular Matrix
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Osteoarthritis
- Phenotype
- Protein Sorting Signals
- Protein Structure, Secondary
- RNA Probes
- RNA, Messenger
- Reference Values