Article
SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations.
Human genetics - 1 Jul 2002
Nath Swapan K, Kelly Jennifer A, Reid Jeff, Lam Tom, Gray-McGuire Courtney, Namjou Bahram, Aston Christopher E, Harley John B
Abstract excerpt
Seizures and psychosis are neuropsychiatric (NP) manifestations of a large number of systemic lupus erythematosus (SLE) patients. Since NP manifestations were part of the SLE phenotype for some, but not all SLE affecteds, we hypothesized that those SLE patient families with NP manifestations might be more genetically homogeneous at loci important to NP-related SLE, and hence have increased power to detect...
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