Article
Association of intermediate T cell receptor cells, mainly their NK1.1(-) subset, with protection from malaria.
Cellular immunology - 10 Jan 2001
Weerasinghe A, Sekikawa H, Watanabe H, Mannoor K, Morshed S R, Halder R C, Kawamura T, Kosaka T, Miyaji C, Kawamura H, Seki S, Abo T
Abstract excerpt
Mice were infected with Plasmodium (P.) yoelii blood-stage parasites. Both the liver and spleen were the sites of inflammation during malarial infection at the beginning of day 7. The major expanding cells were found to be NK1.1(-) intermediate alphabetaTCR (alphabetaTCR(int)) in the liver and spleen, although the population of NK1.1(+) alphabetaTCR(int) cells remained constant or slightly increased. These...
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