Article
A critical role of Fc receptor-mediated antibody-dependent phagocytosis in the host resistance to blood-stage Plasmodium berghei XAT infection.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2001
Yoneto T, Waki S, Takai T, Tagawa Yi, Iwakura Y, Mizuguchi J, Nariuchi H, Yoshimoto T
Abstract excerpt
Plasmodium berghei XAT is an irradiation-induced attenuated variant derived from the lethal strain P. berghei NK65, and its blood-stage parasites are spontaneously cleared in immune competent mice. In the present study, we studied the mechanism of host resistance to blood-stage malaria infection using P. berghei XAT. Infection enhanced Ab-dependent phagocytosis of PRBC by splenic macrophages in wild-type C57BL/6...
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