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Mechanisms underlying the monocyte-mediated antibody-dependent killing of <i>Plasmodium falciparum</i> asexual blood stages

29 Dec 2014

Abstract excerpt

The relevance of the antibody-dependent cellular inhibition (ADCI) of Plasmodium falciparum to clinical protection has been previously established by in vitro studies of material obtained during passive transfer of protection by immunoglobulin G in humans. We here report further in vitro investigations aimed at elucidating the mechanisms underlying this ADCI effect. Results obtained so far suggest that (a)...

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PMID: 7629503
DOI: 10.1084/jem.182.2.40912182014c

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