Article
Development of antimalaria immunity in mice lacking IFN-gamma receptor.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 1995
Tsuji M, Miyahira Y, Nussenzweig R S, Aguet M, Reichel M, Zavala F
Abstract excerpt
IFN-gamma receptor deficient (IFN-gamma R-/-) mice, immunized with different developmental stages of malaria parasites, were used to define the mechanisms of protection against the various stages of this infection. IFN-gamma R-/- mice failed to develop protective immunity against Plasmodium yoeli...
Topics
- Amino Acid Oxidoreductases
- Animals
- Fluorescent Antibody Technique
- Malaria
- Mice
- Mice, Mutant Strains
- Mutation
- Nitric Oxide Synthase
- Plasmodium chabaudi
- Plasmodium yoelii
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Protozoan
- RNA, Ribosomal
- Receptors, Interferon
- Interferon gamma Receptor
