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Article

Development of antimalaria immunity in mice lacking IFN-gamma receptor.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1995

Tsuji M, Miyahira Y, Nussenzweig R S, Aguet M, Reichel M, Zavala F

Abstract excerpt

IFN-gamma receptor deficient (IFN-gamma R-/-) mice, immunized with different developmental stages of malaria parasites, were used to define the mechanisms of protection against the various stages of this infection. IFN-gamma R-/- mice failed to develop protective immunity against Plasmodium yoelii sporozoites or liver stages, upon immunization with a single dose of irradiated sporozoites, whereas in immunized...

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PMID: 7537305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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