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Article

Mechanisms for LEPR-mediated regulation of leptin expression in brown and white adipocytes in rat pups.

Physiological genomics - 19 Jan 2001

Zhang Y, Hufnagel C, Eiden S, Guo K Y, Diaz P A, Leibel R, Schmidt I

Abstract excerpt

To investigate the underlying mechanisms for leptin receptor (LEPR)-mediated regulation of leptin gene (Lep) expression in brown (BAT) and white (WAT) adipose tissue and resultant effects on plasma leptin concentrations (plasma-LEP), we examined effects of sympathetic nervous system (SNS) activity, caloric balance, and body fat content on leptin mRNA levels in BAT and WAT in 10-day-old rat pups segregating for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11160998
DOI: 10.1152/physiolgenomics.2001.4.3.189

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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