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Article

Mutation in the leptin receptor (Leprfa) causes fat-storage-independent hyperleptinaemia in neonatal rats.

Pflugers Archiv : European journal of physiology - 1 Sept 1999

Hufnagel C, Eiden S, Nuesslein-Hildesheim B, Zhang Y, Leibel R, Schmidt I

Abstract excerpt

The plasma leptin concentration adjusted for fat mass is affected by mutant gene dosage in older animals segregating for Leprfa. Because the plasma of neonatal rats contains leptin, although their adipocytes contain virtually no triglyceride, we determined whether mutation dose-dependent differences in plasma leptin concentration exist before the postnatal onset of triglyceride storage. Plasma samples were...

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Source

Identifiers

PMID: 10519153
DOI: 10.1007/s004249900084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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