Article
Phylogenetic evidence for horizontal transfer of mutS alleles among naturally occurring Escherichia coli strains.
Journal of bacteriology - 1 Mar 2001
Brown E W, LeClerc J E, Li B, Payne W L, Cebula T A
Abstract excerpt
mutS mutators accelerate the bacterial mutation rate 100- to 1,000-fold and relax the barriers that normally restrict homeologous recombination. These mutators thus afford the opportunity for horizontal exchange of DNA between disparate strains. While much is known regarding the mutS phenotype, the evolutionary structure of the mutS(+) gene in Escherichia coli remains unclear. The physical proximity of mutS to an...
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