Article
Parameters underlying successful protection with live attenuated mutants in experimental shigellosis.
Infection and immunity - 1 Feb 2001
Bernardini M L, Arondel J, Martini I, Aidara A, Sansonetti P J
Abstract excerpt
Because the use of live attenuated mutants of Shigella spp. represents a promising approach to protection against bacillary dysentery (M. E. Etherridge, A. T. M. Shamsul Hoque, and D. A. Sack, Lab. Anim. Sci. 46:61-66, 1996), it becomes essential to rationalize this approach in animal models in order to optimize attenuation of virulence in the vaccine candidates, as well as their route and mode of administration,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
