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Article

Mechanisms of permeation and selectivity in calcium channels.

Biophysical journal - 1 Jan 2001

Corry B, Allen T W, Kuyucak S, Chung S H

Abstract excerpt

The mechanisms underlying ion transport and selectivity in calcium channels are examined using electrostatic calculations and Brownian dynamics simulations. We model the channel as a rigid structure with fixed charges in the walls, representing glutamate residues thought to be responsible for ion selectivity. Potential energy profiles obtained from multi-ion electrostatic calculations provide insights into ion...

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Identifiers

PMID: 11159395
DOI: 10.1016/S0006-3495(01)76007-9
PMCID: PMC1301226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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