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Article

Genetic contributions of the endothelial nitric oxide synthase gene to ovulation and menopause in a mouse model.

Fertility and sterility - 1 May 2000

Tempfer C, Moreno R M, O'Brien W E, Gregg A R

Abstract excerpt

OBJECTIVE: To investigate the influence of the endothelial nitric oxide synthase gene (Nos3) on ovulatory capacity and reproductive senescence. DESIGN: Prospective, controlled study. SETTING: Academic research institution. SUBJECT(S): Laboratory mice with targeted mutagenesis of Nos3. INTERVENTION(S): Hyperstimulation protocol, oocyte culture, and ovarian histology using wild-type (Nos3(+/+); n = 20),...

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PMID: 10785232
DOI: 10.1016/s0015-0282(00)00417-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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