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Differential expression of mycobacterial proteins following phagocytosis by macrophages

1 Feb 2001

Abstract excerpt

Mycobacterium tuberculosis resides within the macrophages of the host, but the molecular and cellular mechanisms of survival are poorly understood. Recent evidence suggests that the attenuated vaccine strain Mycobacterium bovis BCG is both a deletion and regulatory mutant, yet retains both its immunoprotective and intra-macrophage survival potential. In an attempt to define M. bovis BCG genes expressed during...

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PMID: 11158363
DOI: 10.1099/00221287-147-2-459

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