Article

Epigenetic Crosstalk Between BCG-Infected Macrophages and Naïve Monocytes Potentiates Antimycobacterial Activity

2026-01-12

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of death from infectious disease. Infected cells secrete extracellular vesicles (EVs), nanosized membrane-bound particles containing bioactive molecules known to mediate intercellular communication and influence immune regulation during infection. We hypothesized that EVs secreted from Mycobacterium bovis Bacillus Calmette Gué...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1ef47f8e-9d67-5a1e-8169-d4593652b93e
DOI: 10.64898/2026.01.12.698601

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Crosstalk Between BCG-Infected Macrophages and Naïve Monocytes Potentiates Antimycobacterial ActivityDOI 10.64898/2026.01.12.698601Read

Extracellular Vesicles in Mycobacteria and TuberculosisSemantic proximity Read

Extracellular vesicles in mycobacteria: new findings in biogenesis, host-pathogen interactions, and diagnosticsSemantic proximity Read

Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophagesSemantic proximity Read

Extracellular vesicles in the context of Mycobacterium tuberculosis infectionSemantic proximity Read

Epigenetic Mechanisms Induced by Mycobacterium tuberculosis to Promote Its Survival in the HostSemantic proximity Read

Small RNA sequencing and bioinformatics analysis of RAW264.7-derived exosomes after Mycobacterium Bovis Bacillus Calmette-Guérin infectionSemantic proximity Read

Epigenetic code during mycobacterial infections: therapeutic implications for tuberculosisSemantic proximity Read

Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic accessSemantic proximity Read

Exosomal miR-106b-5p promotes Mtb survival via targeting CREB5 followed by SOAT1-CIDEC and CASP9-CASP3 pathwaySemantic proximity Read

Epigenetic orchestration of host immune defences by Mycobacterium tuberculosisSemantic proximity Read

Hybrid Bacterial Membrane Nanovaccine Reprograms the Tuberculosis Immune Microenvironment via CD40 to Surpass BCG ProtectionSemantic proximity Read

The role of Mycobacterium tuberculosis exosomal miRNAs in host pathogen cross-talk as diagnostic and therapeutic biomarkersSemantic proximity Read