Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global Transcriptional Profile of <i>Mycobacterium tuberculosis</i> during THP-1 Human Macrophage Infection

11 Dec 2007

Abstract excerpt

During lung infection, Mycobacterium tuberculosis resides in macrophages and subverts the bactericidal mechanisms of these professional phagocytes. Comprehension of this host-pathogen relationship is fundamental for the development of new therapies to cure and prevent tuberculosis. In this work, we analyzed the transcriptional profile of M. tuberculosis infecting human macrophage-like THP-1 cells in order to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mycobacterium research and diagnosis
Share to RNA modifications and cancer
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18070897
DOI: 10.1128/iai.00974-07

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global Transcriptional Profile of <i>Mycobacterium tuberculosis</i> during THP-1 Human Macrophage InfectionPMID 18070897Read ↗

Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targetsSemantic proximity Read ↗

Gene expression profiling detects patterns of human macrophage responses following<i>Mycobacterium tuberculosis</i>infectionSemantic proximity Read ↗

Microarray Analysis of Whole Genome Expression of Intracellular Mycobacterium tuberculosisSemantic proximity Read ↗

Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis VirulenceSemantic proximity Read ↗

Gene expression profiling of human macrophages at late time of infection with <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Transcriptional Profiling of Mycobacterium tuberculosis Exposed to<i>In Vitro</i>Lysosomal StressSemantic proximity Read ↗

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and MacrophagesSemantic proximity Read ↗

Apoptosis Genes in Human Alveolar Macrophages Infected with Virulent or Attenuated <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Comparative transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium tuberculosis and Mycobacterium bovis BCGSemantic proximity Read ↗

Mycobacterium tuberculosis Transcription Machinery: Ready To Respond to Host AttacksSemantic proximity Read ↗

Host- and age-dependent transcriptional changes in <i>Mycobacterium tuberculosis</i> cell envelope biosynthesis genes after exposure to human alveolar lining fluidSemantic proximity Read ↗

Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.