Article
Proteins unique to intraphagosomally grown <b> <i>Mycobacterium tuberculosis</i> </b>
20 Mar 2006
Abstract excerpt
Pathogenic mycobacteria persist and replicate within phagosomes of host phagocytes by inhibiting phagosome maturation at an early endosome stage. The molecular basis for this behavior is not understood. To identify proteins of Mycobacterium tuberculosis unique to the intraphagosomal phase, mycobacteria were purified from phagosomes of infected murine bone marrow-derived macrophages and analyzed by high-resolution...
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