Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens

doi:10.1046/j.1365-2958.1999.01549.x

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Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens

1 Sept 1999

Abstract excerpt

In 1993, the WHO declared tuberculosis a global emergency on the basis that there are 8 million new cases per year. The complete genome of the strain H37Rv of the causative microorganism, Mycobacterium tuberculosis, comprising 3924 genes has been sequenced. We compared the proteomes of two non-virulent vaccine strains of M. bovis BCG (Chicago and Copenhagen) with two virulent strains of M. tuberculosis (H37Rv and...

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PMID: 10510226
DOI: 10.1046/j.1365-2958.1999.01549.x

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Comparative proteome analysis of <i>Mycobacterium tuberculosis</i> and <i>Mycobacterium bovis</i> BCG strains: towards functional genomics of microbial pathogens

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