Gene expression profiling of human macrophages at late time of infection with <i>Mycobacterium tuberculosis</i>

doi:10.1111/j.1365-2567.2006.02378.x

Article

Gene expression profiling of human macrophages at late time of infection with <i>Mycobacterium tuberculosis</i>

10 Jul 2006

Abstract excerpt

Macrophages play an essential role in the immune response to Mycobacterium tuberculosis (Mtb). Previous transcriptome surveys, by means of micro- and macroarrays, investigated the cellular gene expression profile during the early phases of infection (within 48 hr). However, Mtb remains within the host macrophages for a longer period, continuing to influence the macrophage gene expression and, consequently, the...

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