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Article

SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading.

Molecular and cellular biology - 1 Feb 2001

Prasad N, Topping R S, Decker S J

Abstract excerpt

In a previous study, we found that the SHIP2 protein became tyrosine phosphorylated and associated with the Shc adapter protein in response to the treatment of cells with growth factors and insulin (T. Habib, J. A. Hejna, R. E. Moses, and S. J. Decker, J. Biol. Chem. 273:18605-18609, 1998). We describe here a novel interaction between SHIP2 and the p130(Cas) adapter protein, a mediator of actin cytoskeleton...

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Share to Cell Adhesion
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Share to Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphoric Monoester Hydrolases

Share to Retinoblastoma-Like Protein p130

Share to src Homology Domains

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Source

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Identifiers

PMID: 11158326
DOI: 10.1128/MCB.21.4.1416-1428.2001
PMCID: PMC99593

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading.PMID 11158326Read ↗

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