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Article

Wild-type circadian rhythmicity is dependent on closely spaced E boxes in the Drosophila timeless promoter.

Molecular and cellular biology - 1 Feb 2001

McDonald M J, Rosbash M, Emery P

Abstract excerpt

Transcriptional regulation plays an important role in Drosophila melanogaster circadian rhythms. The period promoter has been well studied, but the timeless promoter has not been analyzed in detail. Mutagenesis of the canonical E box in the timeless promoter reduces but does not eliminate timeless mRNA cycling or locomotor activity rhythms. This is because there are at least two other cis-acting elements close to...

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Identifiers

PMID: 11158307
DOI: 10.1128/MCB.21.4.1207-1217.2001
PMCID: PMC99574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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