Article
Lymphoblastic crisis of chronic myelogenous leukemia. Hand mirror variant.
Archives of pathology & laboratory medicine - 1 Jul 1990
Kowal-Vern A, Birdsong B A, Dizikes G, Radvany R, Desai S N, Schumacher H
Abstract excerpt
We present, to our knowledge, the first extensively studied case of lymphoid L2 blast crisis of chronic myelogenous leukemia with a hand mirror cell (HMC) variant. Special stains revealed the leukemic cells to be terminal deoxynucleotidyl transferase positive by immunofluorescence and cytochemically positive for alpha-naphthyl acetate esterase and acid phosphatase (diffuse granular). Immunophenotyping identified...
Topics
- Antigens, Neoplasm
- B-Lymphocytes
- Blast Crisis
- Blotting, Western
- Bone Marrow
- Chromosomes
- Erythroblasts
- Gene Rearrangement
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Male