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Article

Overexpression of human amyloid precursor protein in Drosophila.

Molecular cell biology research communications : MCBRC - 1 Jul 2000

Yagi Y, Tomita S, Nakamura M, Suzuki T

Abstract excerpt

Amyloid precursor protein (APP) is the precursor of the beta-amyloid peptide which is associated with Alzheimer's disease. The physiological function of APP is not well understood. We have established model system for the analysis of APP function in Drosophila. In neural cells, overexpressed human APP was transported to the synaptic terminal in a manner similar to its localization in human neurons, which...

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Identifiers

PMID: 11152627
DOI: 10.1006/mcbr.2000.0248

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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