Article
The role of ion-regulatory membrane proteins of excitation-contraction coupling and relaxation in inherited muscle diseases.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2001
Froemming G R, Ohlendieck K
Abstract excerpt
The excitation-contraction-relaxation cycle of skeletal muscle fibres depends on the finely tuned interplay between the voltage-sensing dihydropyridine receptor, the junctional ryanodine receptor Ca2+-release channel and the sarcoplasmic reticulum Ca2+-ATPase. Inherited diseases of excitation-contraction coupling and muscle relaxation such as malignant hyperthermia, central core disease, hypokalemic periodic...
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