Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Soluble HLA-DR antigen levels in serum correlate with rheumatoid arthritis disease activity and the presence of disease-associated epitopes.

Tissue antigens - 1 Nov 2000

Verbruggen L A, Dumarey N, Van de Velde H, Rebmann V, Flament J, Van Wayenberge C, Grosse-Wilde H, Demanet C

Abstract excerpt

We investigated correlations between soluble HLA-DR (sHLA-DR) molecules and several clinical, biological and genetic parameters associated with rheumatoid arthritis (RA) disease activity. Serum sHLA-DR concentrations were determined in 146 samples from 89 RA patients by an ELISA format, using an antibody combination of mouse and rat monoclonal anti-human HLA-DR antibodies. The mean sHLA-DR serum level in RA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes, B-Lymphocyte

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Solubility

Source

Identifiers

PMID: 11144291
DOI: 10.1034/j.1399-0039.2000.560506.x

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Soluble HLA-DR antigen levels in serum correlate with rheumatoid arthritis disease activity and the presence of disease-associated epitopes.PMID 11144291Read ↗

Soluble HLA-G in rheumatoid arthritis.Semantic proximity Read ↗

Specific overexpression of rheumatoid arthritis-associated HLA-DR alleles and presentation of low-affinity peptides.Semantic proximity Read ↗

A routine assay for the direct analysis of HLA-DR-related shared epitope and B27 alleles in chronic inflammatory arthritis.Semantic proximity Read ↗

Distribution of HLA-DR alleles among Thai patients with rheumatoid arthritis.Semantic proximity Read ↗

HLA-DR/DQ interaction in patients with erosive rheumatoid arthritis presenting articular and extraarticular disease manifestations.Semantic proximity Read ↗

HLA-DR alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis.Semantic proximity Read ↗

HLA-DRB1 alleles encoding the "shared epitope" are associated with susceptibility to developing rheumatoid arthritis whereas HLA-DRB1 alleles encoding an aspartic acid at position 70 of the beta-chain are protective in Mexican Mestizos.Semantic proximity Read ↗

HLA-DR antigens and HLA-DQ beta chain polymorphism in susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

The DERAA HLA-DR alleles in patients with early polyarthritis: protection against severe disease and lack of association with rheumatoid arthritis autoantibodies.Semantic proximity Read ↗

Soluble class I HLA antigens in patients with rheumatoid arthritis and their families.Semantic proximity Read ↗

HLA-DRB1 gene transcripts in rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.