Article
APC resistance and third-generation oral contraceptives: Acquired resistance to activated protein C, oral contraceptives and the risk of thromboembolic disease.
Human reproduction (Oxford, England) - 1 Jan 2001
Gris J C, Jamin C, Benifla J L, Quere I, Madelenat P, Mares P
Abstract excerpt
Using a newly-developed technique, a severe acquired plasma resistance to activated protein C has been described in women using third-generation (rather than second-generation) oral contraceptives. The following items are discussed: (i) the technical parameters used to appreciate the effect of activated protein C induce a bias of interpretation, the mean intrinsic effect of activated protein C, in plasmas from...
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