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The VITA project: phenotypic resistance to activated protein C and FV Leiden mutation in the general population. Vicenza Thrombophilia and Atherosclerosis.

Thrombosis and haemostasis - 1 Aug 1997

Tosetto A, Missiaglia E, Gatto E, Rodeghiero F

Abstract excerpt

Resistance to activated protein C (APC) has been recently identified as a common abnormality of the clotting system that significantly increases the risk of venous thromboembolism. The distribution of plasma response to APC in the general population and the variables potentially influencing it ar...

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Cross-Sectional Studies
Drug Resistance
Factor V
ABO gene
APC gene
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9268185

Genes

APC
ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9268185-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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The VITA project: phenotypic resistance to activated protein C and FV Leiden mutation in the general population. Vicenza Thrombophilia and Atherosclerosis.PMID 9268185Read ↗

Activated protein C resistance and the FV:R506Q mutation in a random population sample--associations with cardiovascular risk factors and coagulation variables.Semantic proximity Read ↗

Clinical evaluation of a new functional test for detection of activated protein C resistance (Pefakit APC-R Factor V Leiden) at two centers in Europe and the USA.Semantic proximity Read ↗

Prevalence of activated protein C resistance and analysis of clinical profile in thromboembolic patients. A Belgian prospective study.Semantic proximity Read ↗

Intraindividual consistency of the activated protein C resistance phenotype.Semantic proximity Read ↗

APC resistance: biological basis and acquired influences.Semantic proximity Read ↗

A Retrospective Cross-sectional Study on Activated Protein C Resistance (Factor V Leiden): an Independent, Gender-dependent Risk Factor for Venous ThromboembolismSemantic proximity Read ↗

Laboratory Testing for the Evaluation of Phenotypic Activated Protein C Resistance.Semantic proximity Read ↗

Factor V Leiden and activated protein C resistance.Semantic proximity Read ↗

Activated protein C resistance: the most common risk factor for venous thromboembolism.Semantic proximity Read ↗

Congenital and acquired activated protein C resistance.Semantic proximity Read ↗

Inherited resistance to activated protein C, a major cause of venous thrombosis, is due to a mutation in the factor V gene.Semantic proximity Read ↗

Early days of APC resistance and FV Leiden.Semantic proximity Read ↗

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