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Article

Abnormal intracellular localization of Bax with a normal membrane anchor domain in human lung cancer cell lines.

Japanese journal of cancer research : Gann - 1 Dec 2000

Salah-eldin A, Inoue S, Tsuda M, Matsuura A

Abstract excerpt

Proapoptotic Bax is a member of the Bcl-2 family proteins, which have a key role in regulating programmed cell death. The intracellular localization and redistribution of Bax are important in promoting apoptosis. Bax contains a BH3 domain heterodimerizing with Bcl-2 and a hydrophobic transmembrane segment to be inserted in specified organelle membranes. In this study, Bcl-2 showed cytoplasmic localization in all...

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Identifiers

PMID: 11123426
DOI: 10.1111/j.1349-7006.2000.tb00914.x
PMCID: PMC5926303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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