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Article

Adenine excisional repair function of MYH protein on the adenine:8-hydroxyguanine base pair in double-stranded DNA.

Nucleic acids research - 15 Dec 2000

Shinmura K, Yamaguchi S, Saitoh T, Takeuchi-Sasaki M, Kim S R, Nohmi T, Yokota J

Abstract excerpt

Adenine paired with 8-hydroxyguanine (oh(8)G), a major component of oxidative DNA damage, is excised by MYH base excision repair protein in human cells. Since repair activity of MYH protein on an A:G mismatch has also been reported, we compared the repair activity of His(6)-tagged MYH proteins, expressed in Spodoptera frugiperda Sf21 cells, on A:oh(8)G and A:G mismatches by DNA cleavage assay and gel mobility...

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Identifiers

PMID: 11121482
DOI: 10.1093/nar/28.24.4912
PMCID: PMC115236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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