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Article

Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts.

Journal of translational medicine - 9 May 2018

Gary Regina, Aigner Michael, Moi Stephanie, Schaffer Stefanie, Gottmann Anja, Maas Stefanie, Zimmermann Robert, Zingsem Jürgen, Strobel Julian, Mackensen Andreas, Mautner Josef, Moosmann Andreas, Gerbitz Armin

Abstract excerpt

BACKGROUND: A major complication after allogeneic hematopoietic stem cell transplantation (aSCT) is the reactivation of herpesviruses such as cytomegalovirus (CMV) and Epstein-Barr virus (EBV). Both viruses cause significant mortality and compromise quality of life after aSCT. Preventive transfer of virus-specific T cells can suppress reactivation by re-establishing functional antiviral immune responses in...

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Share to Cytomegalovirus
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoietic Stem Cell Mobilization

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Share to Herpesvirus 4, Human

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Source

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Identifiers

PMID: 29743075
DOI: 10.1186/s12967-018-1498-3
PMCID: PMC5941463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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