Article
Ex vivo generation of cytokine-induced killer cells (CD3+ CD56+) from post-stem cell transplant pediatric patients against autologous-Epstein-Barr virus-transformed lymphoblastoid cell lines.
Pediatric transplantation - 1 Aug 2007
Petvises Sawang, Pakakasama Samart, Wongkajornsilp Adisak, Sirireung Somtawin, Panthangkool Wanpen, Hongeng Suradej
Abstract excerpt
EBV-PTLDs affect as high as 20% of SCT recipients especially those with T-cell depleted grafts while high mortality rates were also noted. Adoptive allogeneic and autologous CTLs have a therapeutic potential in this setting. However, the process of expansion of these cells is tedious and time con...
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