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Article

Expansion of EBNA1-specific effector T cells in posttransplantation lymphoproliferative disorders.

Blood - 30 Sept 2010

Jones Kimberley, Nourse Jamie P, Morrison Leanne, Nguyen-Van Do, Moss Denis J, Burrows Scott R, Gandhi Maher K

Abstract excerpt

Immunosuppression resulting in impaired Epstein-Barr virus (EBV)-specific T-cell immunity is involved in the pathogenesis of EBV-positive post-transplantation lymphoproliferative disorder (EBV(+) PTLD). Restoration of EBV-specific T-cell immunity by adoptive immunotherapy can induce remission. EBV-nuclear antigen-1 (EBNA1) is unique in being expressed in all cases of EBV(+) PTLD. Recent data demonstrate that...

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Source

Identifiers

PMID: 20562330
DOI: 10.1182/blood-2010-03-274076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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