Article
Association of angiotensin II type 1 receptor gene polymorphism with essential hypertension.
Clinical genetics - 1 Jan 1997
Wang W Y, Zee R Y, Morris B J
Abstract excerpt
The renin-angiotensin system is involved in control of blood pressure and salt and fluid homeostasis. Genes for components of this system have been of major focus in research on the causation of the common, complex, polygenic trait, essential hypertension (HT). Association of an A-->C variant at nucleotide 1166 of the angiotensin II type 1 receptor (AT1R) gene with HT, but an absence of linkage of this locus with...
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