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[Single nucleotide polymorphisms of three candidate genes in essential hypertension].

Zhonghua nei ke za zhi - 1 Apr 2006

Hu Bang-chuan, Chu Shao-li, Wang Ji-guang, Wang Gu-liang, Gao Ping-jin, Zhu Ding-liang

Abstract excerpt

OBJECTIVE: To explore the association of single nucleotide polymorphisms (SNPs) of three candidate genes, including T869C of transforming growth factor beta1 (TGF-beta1), -344T/C of aldosterone synthase (CYP11B2) and Gly460Trp of alpha-Adducin with essential hypertension in Chinese Han population. METHODS: Three hundred ninety six hypertensive patients and 214 normotensive subjects were genotyped for T869C,...

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PMID: 16780672

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