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Article

Combgap relays wingless signal reception to the determination of cortical cell fate in the Drosophila visual system.

Molecular cell - 1 Nov 2000

Song Y, Chung S, Kunes S

Abstract excerpt

The dorsoventral axis of the Drosophila visual cortex is patterned by nonautonomous signals expressed at its dorsal and ventral margins. wingless (wg) expression at the margins induces decapentaplegic (dpp), optomotor blind (omb), and aristaless in adjacent domains. We show that Combgap, a zinc finger protein, represses Wg target gene expression in the visual cortex. Wg signal reception downregulates combgap...

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Identifiers

PMID: 11106753
DOI: 10.1016/s1097-2765(00)00112-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Combgap relays wingless signal reception to the determination of cortical cell fate in the Drosophila visual system.PMID 11106753Read ↗

Transcriptional regulation of the Hedgehog effector CI by the zinc-finger gene combgap.Semantic proximity Read ↗

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Antagonistic regulation of the second mitotic wave by Eyes absent-Sine oculis and Combgap coordinates proliferation and specification in the Drosophila retina.Semantic proximity Read ↗

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Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing.Semantic proximity Read ↗

Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos.Semantic proximity Read ↗

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